http://localhost:8080/xmlui/handle/123456789/3 2026-04-05T18:12:39Z 2026-04-05T18:12:39Z Okeke, Chinedu Eseigbe, Patricia http://localhost:8080/xmlui/handle/123456789/2956 2024-10-15T09:27:24Z 2022-10-21T00:00:00Z

Attitude and Knowledge of Voluntary Non-Remunerated Blood Donation among Clinical Medical Students in a Tertiary Institution in North-Central Nigeria Okeke, Chinedu; Eseigbe, Patricia Background: Blood transfusion is an important component of the management of patients with various medical and surgical conditions. Blood is scarce and the efficiency of blood transfusion service relies on the availability of safe blood from voluntary non-remunerated donors. Medical students can serve as models to inculcate the habit of blood donation among other students and be a steady pool of voluntary blood donors. This study was to assess the knowledge, attitude, and practice of voluntary blood donation among clinical medical students in a private tertiary institution in the North-Central Zone of Nigeria. Methods: This was a descriptive cross-sectional study involving the clinical students of Bingham University Jos, Nigeria. Selfadministered structured questionnaires were used to collect the data. Data were analyzed using SPSS version 25. Results: A total of 304 clinical students participated in the study. The mean age of the respondents was 22.9 years with a standard deviation of 2.3years. Female participants were 163 (53.6%). Most of the respondents 206 (67.8%) had good knowledge of blood donation. The majority 254 (83.6%) of respondents had a good attitude toward voluntary blood donation. Most 226 (74. 3%) responded positively towards voluntary blood donation; however, only 98 (32. 2%) had ever donated blood. Most of the respondents who donated blood did it just once 62 (20.3%). The commonest reason for inertia to voluntary blood donation was fear of dizziness and fainting attacks 106 (34.9%). Many of the respondents would be motivated to donate blood if drinks 155 (51%) and food 151 (49.7%) were offered. There was a significant association between knowledge of blood donation and the participants’ gender (p = 0.038), class in medical school (p = 0.001), and their attitude (p = 0.001) to voluntary non-remunerated blood donation. Conclusion: The medical students had good knowledge and a good attitude toward voluntary non-remunerated blood donation. Although the majority expressed a good attitude towards voluntary blood donation, the practice was poor. Increased awareness and education about voluntary blood donation among medical students can increase the number of voluntary blood donors in Nigeria. In addition, the provision of food and drinks in blood donation stations can serve as motivation for voluntary blood donors.

2022-10-21T00:00:00Z Okeke, Chinedu Ode, Charity http://localhost:8080/xmlui/handle/123456789/2955 2024-10-11T11:21:26Z 2023-07-20T00:00:00Z

Frequency of Red Cell Alloantibodies among Pregnant Women Receiving Antenatal Care in a Tertiary Health Facility in Jos, Nigeria Okeke, Chinedu; Ode, Charity Aims: To determine the frequency of red blood cell alloantibodies among pregnant women in Jos, Nigeria. Study Design: A cross sectional study was carried out among pregnant women accessing antenatal care. Place and Duration of Study: The study was conducted at Department of Obstetrics and Gynaecology and Department of Haematology and Blood Transfusion, Jos University Teaching Hospital (JUTH) Jos, Nigeria from 24th April 2017 to 31st May 2017. Methodology: We included 200 pregnant women accessing antenatal care. Data on clinical details were obtained with an Interviewer-administered questionnaire. Screening and identification of red blood cell alloantibodies were made using the DiaCells, and DiaPanels (DiaMed GmbH, Switzerland). ABO and Rh blood groups were done using antisera from Biotec (Ipswich, UK). Results: Out of 200 participants, alloantibodies were found in 24 (12.0%) of participants and their specificities were as follows; anti-E, 9 (4.5%); anti- e, 1 (0.5%); anti-C, 6 (3.0%); anti- c, 2 (1.0%); anti- K, 2 (1.0%); anti- P, 1 (0.5%); anti- N, 1 (0.5%), while 2 (1.0%) showed a combination of antibodies of whose specificities could not be determined by the Diamed 11-panel cells. Multigravidity was identified as a risk factor for alloimmunization (P= 0.01). However, alloimmunization status was independent of previous abortions, trimester of pregnancy, and ABO blood group of the studied population. Conclusion: Alloantibody screening and identification should be included in routine antenatal care, especially for at-risk populations.

2023-07-20T00:00:00Z Onubi, Jeremiah Adeola, Oluwagbenga Adebayo Eseigbe, Patricia Elisha, Adesegun Harrison, Christian C. Nwankwo, Chizoba G. Chima, Anyuku A.G. http://localhost:8080/xmlui/handle/123456789/2875 2024-09-23T13:05:48Z 2024-08-01T00:00:00Z

Levels and Predictors of Unsuppressed Viremia among People Living with HIV on ART in an Urban Population of North-Central Nigeria: A Retrospective Cross-sectional Study. Onubi, Jeremiah; Adeola, Oluwagbenga Adebayo; Eseigbe, Patricia; Elisha, Adesegun; Harrison, Christian C.; Nwankwo, Chizoba G.; Chima, Anyuku A.G. Achieving viral suppression is crucial for the effective management of HIV. We investigated the prevalence and predictors of unsuppressed viremia among adults living with HIV (PLHIV) on antiretroviral therapy (ART) in the urban city of Jos, Plateau State, North-central Nigeria. A cross-sectional study was conducted with 2,748 PLHIV, comprising 1,902 females (69.2%) and 846 males (30.8%). The majority (71.0%) were aged 36-55 years. Most participants (88.1%) were on the first-line ART regimen tenofovir disoproxil fumarate-lamivudine-dolutegravir (TDF+3TC+DTG), with 6.0% on second-line regimens. The prevalence of unsuppressed viremia (viral load >1,000 copies/mL) was assessed, and predictors were identified using chi-square tests and logistic regression analyses. Overall prevalence of unsuppressed viremia was 4.0% (110 participants), with higher proportions among males (5.6%) compared to females (3.3%) and among those aged 18-35 years (7.9%) compared to other age groups. PLHIV on first-line TDF+3TC+DTG ART had the lowest level of unsuppressed viremia (2.6%). Chi-square tests revealed significant associations between unsuppressed viremia and gender (χ2=7.67, p=0.01), age group (χ2=13.19, p=0.01), and ART regimen (χ2=110.97, p=0.0001). Multivariate logistic regression identified males (AOR=1.69; 95% CI: 1.12-2.56), younger age groups (18-35 years: AOR=12.96; 95% CI: 2.12-79.09 and 36-45 years: AOR=12.84; 95% CI: 3.70-44.64), and non-TDF+3TC+DTG regimens as significant predictors of unsuppressed viremia. The study highlights the effectiveness of the TDF+3TC+DTG regimen and the need for targeted interventions to address disparities in viral suppression, particularly among males and younger individuals. These findings are crucial for optimizing HIV treatment strategies and improving health outcomes for PLHIV in urban areas of low-and-middle-income countries.

2024-08-01T00:00:00Z Onubi, Jeremiah Adeola, Oluwagbenga Adebayo Eseigbe, Patricia Elisha, Adesegun Sheyin, Grace Chima, Anyuku A.G. http://localhost:8080/xmlui/handle/123456789/2874 2024-09-23T13:04:56Z 2024-09-01T00:00:00Z

Sociodemographic Factors Associated with Depression among People Living with Human Immunodeficiency Virus on Antiretroviral Therapy at a University Teaching Hospital in a Nigerian Cosmopolitan City. Exploratory Research and Hypothesis in Medicine Onubi, Jeremiah; Adeola, Oluwagbenga Adebayo; Eseigbe, Patricia; Elisha, Adesegun; Sheyin, Grace; Chima, Anyuku A.G. Background and objectives: Depression can lead to poor outcomes during antiretroviral therapy, and current evidence suggests high rates of depression among people living with human immunodeficiency virus (PLHIV), especially in low-and middle-income countries. This study was designed to investigate the sociodemographic factors associated with depression among PLHIV on antiretroviral therapy in a Nigerian cosmopolitan city. Methods: A hospital-based, cross-sectional study was conducted among 592 consenting, randomly selected adult PLHIV receiving treatment at a university teaching hospital in Jos, Nigeria, in 2022, using the PHQ-9 questionnaire and an intervieweradministered sociodemographic questionnaire. Associated variables in univariate analysis were used in multivariable binary logistic regression to obtain adjusted odds ratios (AOR) with a significance level set at α = 0.05. Results: Depression was found to be highly prevalent among study participants, with 44.9% of them affected. Findings revealed that being male [AOR = 0.62; 95% confidence interval (CI): 0.42–0.92], being employed (AOR = 0.55; 95%CI: 0.31–0.97), and earning a monthly income of ₦50,000–100,000 ($65–130) (AOR = 0.49; 95% CI: 0.27–0.91) and >₦100,000–200,000(>$130–260) (AOR = 0.33; 95% CI: 0.13–0.77) were significantly associated with reduced odds of depression. Conclusions: The significant association of being male, having formal employment, and earning a moderate monthly income with reduced odds of depression may have implications for policy and strategies for managing mental health issues among PLHIV in cosmopolitan areas like Jos, which face peculiar challenges such as cultural tensions, traffic congestion, and gentrification. PLHIV categories with a relatively higher likelihood of depression may benefit from targeted mental health support systems, in addition to other mental health management strategies generally available to PLHIV.

2024-09-01T00:00:00Z