<?xml version="1.0" encoding="UTF-8"?>
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<title>Department of Pharmaceutical Chemistry</title>
<link href="http://localhost:8080/xmlui/handle/123456789/575" rel="alternate"/>
<subtitle/>
<id>http://localhost:8080/xmlui/handle/123456789/575</id>
<updated>2026-04-05T19:47:29Z</updated>
<dc:date>2026-04-05T19:47:29Z</dc:date>
<entry>
<title>Elemental analysis of spring onion grown around the industrial area of Jos-South local government and sold as food in Bukuru market of Plateau State, Nigeria</title>
<link href="http://localhost:8080/xmlui/handle/123456789/1352" rel="alternate"/>
<author>
<name>Famojuro, Tayo I.</name>
</author>
<author>
<name>Datok, Tongret</name>
</author>
<author>
<name>Ogira, J.O</name>
</author>
<id>http://localhost:8080/xmlui/handle/123456789/1352</id>
<updated>2024-05-23T11:37:23Z</updated>
<published>2023-01-01T00:00:00Z</published>
<summary type="text">Elemental analysis of spring onion grown around the industrial area of Jos-South local government and sold as food in Bukuru market of Plateau State, Nigeria
Famojuro, Tayo I.; Datok, Tongret; Ogira, J.O
There is an increased risk of consuming vegetables and fruits grown around industrial areas globally.&#13;
Scientific documentation of evidence of the high risk of heavy metals that may be absorbed by these&#13;
plants should be made public. Heavy metals such as copper (Cu), zinc (Zn), cadmium (Cd), iron (Fe),&#13;
nickel (Ni), and Lead (Pb), alkaline metals such as sodium (Na) and potassium (K), and alkaline earth&#13;
metal like calcium (Ca) were analysed using atomic absorption flame photometer from a sample of&#13;
spring onions planted and harvested around the industrial area of Jos-South Local Government and sold&#13;
for consumption in Bukuru market of Plateau State, Nigeria. Results showed that zinc, iron, nickel,&#13;
copper, sodium and calcium were found in toxic concentrations, potassium level was reduced, while lead&#13;
and cadmium levels were below detection levels when the values were compared to the official&#13;
recommended standard for daily body intake. Vegetables should be consumed from safe areas of&#13;
cultivation as contaminations with heavy metals may result in serious metal poisoning
</summary>
<dc:date>2023-01-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>ISOLATION AND CHARACTERIZATION OF INCENSOLE AND DA‐23‐IV (NEPHTHENOL) FROM ETHYL ACETATE STEM BARK EXTRACT OF PSEUDOCEDRELA KOTSCHYI SCHEINF HARMS (MELIACEAE)</title>
<link href="http://localhost:8080/xmlui/handle/123456789/1351" rel="alternate"/>
<author>
<name>Ogira, J.O</name>
</author>
<id>http://localhost:8080/xmlui/handle/123456789/1351</id>
<updated>2024-05-23T11:35:48Z</updated>
<published>2023-11-01T00:00:00Z</published>
<summary type="text">ISOLATION AND CHARACTERIZATION OF INCENSOLE AND DA‐23‐IV (NEPHTHENOL) FROM ETHYL ACETATE STEM BARK EXTRACT OF PSEUDOCEDRELA KOTSCHYI SCHEINF HARMS (MELIACEAE)
Ogira, J.O
Pseudocedrela kotschyi Schweinf Harms (Meliaceae) is used in ethnomedicine to treat various disease conditions (like ulcers, sores, rheumatism,&#13;
leprosy, syphilis, fevers and tumors. The dried pulverized bark material was extracted using maceration method with methanol. The methanolic&#13;
extract obtained was fractionated into water, hexane and ethyl acetate fractions. Repeated Column chromatography and preparative thin-layer&#13;
chromatography (TLC) of the ethyl acetate fraction yielded two pure compounds, incensole and nephthenol. The structures of the isolated&#13;
compounds were elucidated using nuclear magnetic resonance spectroscopy (1D and 2D 1&#13;
HNMR and 13CNMR). This is the first time report of&#13;
Incensole a cembrane diterpenoid compound in the stem bark of the plant P. kotschyi..
</summary>
<dc:date>2023-11-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>60-Day Assessment of Mr. Flush® Cleanser on Hematological indices and Kidney Histoarchitecture in Exposed Wistar Rats</title>
<link href="http://localhost:8080/xmlui/handle/123456789/1348" rel="alternate"/>
<author>
<name>Uduak, Peter Ise</name>
</author>
<author>
<name>Famojuro, Tayo I.</name>
</author>
<author>
<name>Johnson, O.J</name>
</author>
<author>
<name>Sebastine, A. Z.</name>
</author>
<author>
<name>Ibrahim, A.M.</name>
</author>
<author>
<name>Williams, Ujah</name>
</author>
<author>
<name>Builders, M.I</name>
</author>
<id>http://localhost:8080/xmlui/handle/123456789/1348</id>
<updated>2024-05-23T11:33:47Z</updated>
<published>2023-01-01T00:00:00Z</published>
<summary type="text">60-Day Assessment of Mr. Flush® Cleanser on Hematological indices and Kidney Histoarchitecture in Exposed Wistar Rats
Uduak, Peter Ise; Famojuro, Tayo I.; Johnson, O.J; Sebastine, A. Z.; Ibrahim, A.M.; Williams, Ujah; Builders, M.I
ct&#13;
Aim: there is a surge in herbal product sales with less adequate information on their safety. The toxicity concerns of Mr.&#13;
Flush® polyherbal formulation on hematological and biochemical parameters was investigated in Wistar rats.&#13;
Methodology: Thirty Wistar rats of both genders were randomly allotted to six groups (5 per group) and treated by oral&#13;
administration daily thus: Groups 1 and 2-Controls (distilled water, 10 mL/kg), Groups 3-4; 5-6 received the Polyherbal&#13;
mixture (374, 748) mg/kg, respectively. On 62nd day, animals were euthanized under diethyl ether anesthesia and&#13;
sacrificed. Blood samples were collected using cardiac puncture for biochemical evaluation. Eviscerated liver and kidneys&#13;
were weighed and fixed in 10% formalin for histopathological examination.&#13;
Results: The LD50 of the Polyherbal Formulation was estimated to be 3740.17 mg/kg (mouse per oral). Results were&#13;
considered significant at p ≤0.05. There was significant increase in blood platelets (PLT) in low dosed and high dosed&#13;
groups compared with control, WBCs increased in treatment groups compared with controls. Kidney function parameters&#13;
such as Urea and Creatinine were elevated in all treatment groups compared to control. Histopathology of the kidneys&#13;
revealed degrees of pathologies such as occluding Bowman’s space, widened proximal and distal convoluted tubules,&#13;
hyperplasia of cortical tissue cells as well as hyperplasia of tubular and connective tissue cells
</summary>
<dc:date>2023-01-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>Effect of the Demographic of Covid-19 on Different Countries; Using the USA for Comparism</title>
<link href="http://localhost:8080/xmlui/handle/123456789/1345" rel="alternate"/>
<author>
<name>Joseph, Oyepata Simeon</name>
</author>
<author>
<name>Builders, Modupe</name>
</author>
<author>
<name>Famojuro, Tayo Ibukun</name>
</author>
<author>
<name>Ogira, Johnson Ogwuche</name>
</author>
<id>http://localhost:8080/xmlui/handle/123456789/1345</id>
<updated>2024-05-23T11:30:33Z</updated>
<published>2021-02-01T00:00:00Z</published>
<summary type="text">Effect of the Demographic of Covid-19 on Different Countries; Using the USA for Comparism
Joseph, Oyepata Simeon; Builders, Modupe; Famojuro, Tayo Ibukun; Ogira, Johnson Ogwuche
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome&#13;
coronavirus. The virus that causes COVID-19 spreads mainly when an infected person is in close contact with another person. The&#13;
aim of this study is to determine the effect of COVID-19 on different countries, using USA as comparism factor. Ninety four&#13;
countries were selected based on their continents, countries and cases of infection. Data from each country were obtained from&#13;
United Nations Geoscheme and WHO and were analyzed and compared to that of the United State of America (USA).Data analyzed&#13;
revealed that most countries in Africa appears to be least affected by the virus. Data also revealed that many countries have been&#13;
able to understand and manage the spread and infectivity of the virus compared to the USA. Result from the study also showed&#13;
that the many countries have been able to improve on managing the infection when compared to USA mortality. This may be due&#13;
to among other factors a more robust immune response, herd immunity and united approach in the management of the disease.&#13;
The result also helps to provide insight as to how significant developing and providing vaccine may be to this part of the world.&#13;
Result from the study suggests that while Africa has a better immunity for the virus, there seems to be improvement the&#13;
management of disease by other continent.
</summary>
<dc:date>2021-02-01T00:00:00Z</dc:date>
</entry>
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